Tissue engineering is no quick fix for kidney disease, but early intervention can help

Kidney disease often lacks symptoms until it is at an advanced stage.

by Frieda Klotz Recent advances in kidney research have yielded dramatic headlines touting scientists’ ability to grow kidneys in the lab. But some experts worry that hype about tissue engineering is excessively raising patients’ hopes. In 2013, US scientists announced that they had grown kidneys that could process urine in rats. The announcement was hailed as potentially … Read more

3D-printed living tissues could spell the end of arthritis

Arthritis breaks down the cartilage between joints, leading to pain, stiffness and swelling.

by Ethan Bilby Bioinks containing stem cells are being used to 3D print living tissues that can be inserted into the body and provoke a damaged joint to heal itself. It’s a development that could reduce the discomfort and pain of the one in 10 people who will suffer from arthritis over their lifetime. Arthritis … Read more

Europe is in danger of being out-innovated in regenerative medicine – Prof. Ton Rabelink

With the right environments, stem cells can potentially be reprogrammed to grow kidney tissue.

by Frieda Klotz Regenerative medicine should be governed, firstly, by the principle of do no harm, but a better balance between risk and regulation is required to bring innovations to market more quickly, according to Ton Rabelink, professor of internal medicine and head of nephrology at Leiden University in the Netherlands. He says that Europe is in … Read more

Cell factories mass-produce living drugs

The CliniMACS Cell Factory at Miltenyi Biotec's facilities in Germany automates the production of cell therapy for patients with blood cancer.

Table-top cell production factories and placentas harvested after birth are promising to bring life-saving cell therapies to unprecedented numbers of patients. The techniques could potentially help to turn the tide on chronic diseases and certain forms of cancer by providing much-needed upscaling for regenerative medicine. ‘You insert the blood here, press the button, follow the steps and … Read more

Discovery of hybrid cancer cells reveals how disease spreads

Studies show that hybrid cancer cells (in yellow) combine properties of different cells which can make them more invasive.

Scientists studying skin and breast cancer in genetically modified mice have spotted hybrid cancer cells that combine the properties of different cell types, a discovery that could help understand how cancer spreads in the body and provide a new target for treatment. It is the latest insight in a fast-moving research area that is revealing … Read more

Want to cure disease? Repurpose the body’s cells

Implanting stem cells from elsewhere in the body can help reverse organ damage.

If one part of the body breaks, can you just replace it with cells from another organ? That’s the hope of stem cell scientists who are reprogramming cells to treat major conditions such as incontinence and heart failure. Millions of Europeans are affected by stress urinary incontinence (SUI) which can have a devastating effect on … Read more