Rise in vaccine hesitancy related to pursuit of purity – Prof. Heidi Larson

Europe is the most sceptical region in the world when it comes to vaccines, according to the vaccine confidence index.

The rise of alternative health practices and a quest for purity can partly explain the falling confidence in vaccines which is driving outbreaks of preventable diseases such as measles, according to Heidi Larson, professor of anthropology, risk and decision medicine at the UK’s London School of Hygiene & Tropical Medicine. She is working to understand … Read more

Large surface area lends superpowers to ultra-porous materials

Metal-organic frameworks as seen under an electron microscope are made up of crystals that together shape multi-dimensional structures with vast surface areas. Image credit - CSIRO/ Dr Paolo Falcaro, Dr Dario Buso, licensed under CC BY 3.0 (color changed)

Some materials are special not for what they contain, but for what they don’t contain. Such is the case with metal-organic frameworks (MOFs) – ultra-porous structures that are being developed for a variety of future applications from fire-proofing to drug-delivery. MOFs are, in fact, the most porous materials known to humankind. One metal-organic framework, so-called NU-110, has … Read more

Lab-grown tissues to improve reliability of safety tests for drugs, chemicals

This human liver organoid gives researchers hope that animal-based studies about drug safety will be a method of the past one day.

by Natalie Grover Testing the safety of medicines and chemicals on organ-like structures developed from various types of stem cells could reduce the reliance on animal testing and streamline chemical and drug development, according to scientists in the Netherlands who are in the early stages of developing such technology.  Tissues such as the intestine and … Read more

Europe’s silent opioid epidemic

Codeine addiction is a widespread problem which can be hard to diagnose, study says.

As opiate addiction continues to grip the United States – killing more than 100 people per day in 2016 – researchers are trying to get a handle on the scale of the problem in Europe. The US is grappling with a major crisis driven by dependency on opioid painkillers such as fentanyl. These highly addictive prescription drugs are … Read more

Omics, sweet omics – curing the incurable, one disease at a time

In recent years, the genetic defects behind about 5,000 of the estimated 7,000-8,000 rare diseases have been discovered, largely thanks to omics.

There are many rare genetic diseases that strike perhaps only one in a million people. Often incurable, they can be profoundly debilitating and frequently life-threatening. Though each particular disease is rare, they number in the thousands – which means that together they affect about 30 million Europeans or around 7% of us. Treating these diseases is challenging … Read more